Through games of Jan. 15, 2006:
| # | Team | W-L | Pts. | Last Week |
| 1 | Southern Maine (21) | 14-1 | 617 | 1 |
| 2 | Washington U. (1) | 13-1 | 568 | 4 |
| 3 | Scranton (1) | 14-1 | 554 | 5 |
| 4 | George Fox | 14-1 | 477 | 6 |
| 5 | Mary Washington (2) | 14-0 | 470 | 7 |
| 6 | Wheaton (Ill.) | 12-1 | 468 | 8 |
| 7 | Brandeis | 10-1 | 467 | 2 |
| 8 | Bowdoin | 12-2 | 453 | 3 |
| 9 | Capital | 14-1 | 438 | 10 |
| 10 | DePauw | 15-1 | 428 | 9 |
| 11 | Hope | 14-1 | 423 | 11 |
| 12 | Baldwin-Wallace | 13-2 | 332 | 12 |
| 13 | Messiah | 14-1 | 327 | 13 |
| 14 | McMurry | 14-0 | 291 | 16 |
| 15 | Randolph-Macon | 10-2 | 263 | 15 |
| 16 | Moravian | 13-1 | 210 | 17 |
| 17 | Calvin | 12-2 | 197 | 14 |
| 18 | New York University | 12-1 | 184 | 20 |
| 19 | Salem State | 10-1 | 178 | 21 |
| 20 | Chicago | 13-1 | 130 | 22 |
| 21 | Richard Stockton | 11-1 | 91 | 18 |
| 22 | Mississippi College | 11-1 | 85 | 25 |
| 23 | Hardin-Simmons | 11-2 | 72 | — |
| 24 | UW-La Crosse | 14-2 | 67 | 19 |
| 25 | Pacific Lutheran | 13-1 | 64 | — |
Dropped out: No. 23 Washington and Jefferson; No. 24 Oglethorpe
Others receiving votes: St. Benedict 57, Washington and Jefferson 31, Bates 26, Trinity (Texas) 24, Rochester 23, Wilmington 22, Luther 18, Carroll 18, Oglethorpe 14, Millikin 12, UW-Oshkosh 11, Simpson 4, Clark 3, Catholic 2, Williams 2, Franklin 2, Thomas More 1, Lawrence 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.